Fluorescent In Situ hybridization, FISH

Fluorescent In Situ hybridization (FISH)

What is FISH?

How does FISH work?

What is FISH used for?

How many types of probes for FISH?

Our Services and Products

Citations/References

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What is FISH? [ TOP ]

Fluorescence in situ hybridization (FISH) is a molecular diagnostic technique utilizing fluorescently labeled DNA probes to detect or confirm gene or chromosome abnormalities. The sample DNA (metaphase chromosomes or interphase nuclei) is first denatured, a fluorescently labeled probe of interest is then added to the denatured sample mixture and hybridizes with the sample DNA at the target site as it re-anneals back into a double helix. The probe signal can then be seen through a fluorescent microscope and the sample DNA can be scored for the presence or absence of the signal. Unlike most other techniques used to study chromosomes, FISH does not have to be performed on cells that are actively dividing. This makes it a very versatile procedure.

Fluorescent In Situ hybridization
FISH
[From National Human Genome Research Institute]

How does FISH work? [ TOP ]

FISH is useful, for example, to help a researcher identify where a particular gene falls within an individual's chromosomes. Here's how it works:

o Make a probe complementary to the known sequence. When making the probe, label it with a fluorescent marker, e.g. fluorescein, by incorporating nucleotides that have the marker attached to them.

o Put the chromosomes on a microscope slide and denature them.

o Denature the probe and add it to the microscope slide, allowing the probe hybridize to its complementary site.

o Wash off the excess probe and observe the chromosomes under a fluorescent microscope. The probe will show as one or more fluorescent signals in the microscope, depending on how many sites it can hybridize to

[ Andre M. Oliveira et al ]

What is FISH used for? [ TOP ]

FISH is widely used for several diagnostic applications: identification of numerical and structural abnormalities, characterization of marker chromosomes, monitoring the effects of therapy, detection of minimal residual disease, tracking the origin of cells after bone marrow transplantation, identification of regions of deletion or amplification, detection of chromosome abnormalities in non-dividing or terminally differentiated cells, determination of lineage involvement of clonal cells… Moreover it has many applications in research: identification of non-random chromosome rearrangements, identification of translocation molecular breakpoint, identification of commonly deleted regions, gene mapping, characterization of somatic cells hybrids, identification of amplified genes, study the mechanism of rearrangements. FISH is also used to compare the genomes of two biological species to deduce evolutionary relationships.

How many types of probes for FISH? [ TOP ]

Generally, researchers use three different types of FISH probes, each of which has a different application:

Locus specific probes bind to a particular region of a chromosome. This type of probe is useful when researchers have isolated a small portion of a gene and want to determine on which chromosome the gene is located.

Alphoid or centromeric repeat probes are generated from repetitive sequences found in the middle of each chromosome. Researchers use these probes to determine whether an individual has the correct number of chromosomes. These probes can also be used in combination with "locus specific probes" to determine whether an individual is missing genetic material from a particular chromosome.

Whole chromosome probes are actually collections of smaller probes, each of which binds to a different sequence along the length of a given chromosome. Using multiple probes labeled with a mixture of different fluorescent dyes, scientists are able to label each chromosome in its own unique color. The resulting full-color map of the chromosome is known as a spectral karyotype. Whole chromosome probes are particularly useful for examining chromosomal abnormalities, for example, when a piece of one chromosome is attached to the end of another chromosome.

Our Services and Products: [ TOP ]

Creative Biolabs offers a full array of custom Fluorescence in situ hybridization (FISH) service from probe design, chromosome/cell preparation to expert result interpretation.

Chromosome/Cell Preparation: We can help you performing cell chromosome FISH (FISH on interphase, metaphase and cultured cells), tissue chromosome FISH (FISH on formalin-fixed, paraffin-embedded tissue or cell slides) and RNA-FISH (FISH to study intracellular RNA localization, RNA processing, quantitation). We performed numerous tests aimed to improve the efficiency of cytogenetic slide preparation and to increase FISH signals. Several modifications of the general protocol resulted in better chromosome spreading, better chromosome morphology and shorter hybridization times, while yielding brighter FISH signals.

Probes Design, Labeling, Purification and Test: Our FISH probes are synthetic pieces of DNA that couple with a fluorescent indicator, so that the chromosomes or genes that they bind to can be directly visualized under our imaging analysis system. Our well-established standard operating procedure allows efficient optimization of labeling a variety of fluorescent probes. Also, we can provide experimental services to meet your special needs. Customized probes are available as well. The choice of directly or indirectly labeled SpectrumOrange, SpectrumGreen, or SpectrumAqua probes is dependent upon the use and combination of other fluorophores in the FISH assay.

o Whole chromosome painting probes (WPP)
o Chromosome arm painting probes (APP)
o Chromosome terminal band painting probes (TPP)
o Chromosome enumeration probes (CEP)
o Chromosome subtelomere probes (CSP)
o chromosome loci specific probes (CLP)

In Situ Hybridization: We can optimize the FISH hybridization conditions and provide a full array of FISH services.

Result Interpretation: Our FISH imaging analysis system consists of a fluorescent microscope, a charge-coupled-device (“CCD”) camera and imaging analysis software. All three components are provided by our component suppliers with internal modifications. Through the use of FISH probes, the imaging analysis system enables medical practitioners to detect and localize the presence or absence of specific DNA sequences in chromosomes.

Prenatal Diagnosis: Our optimized prenatal diagnosis detection kits offer innovative technologies and standard methods that are applied to the diagnosis of fetal disorders.

o Trisomy (21/18/13/12/9/8)
o Turner Syndrome
o Trisomy X
o XYY Syndrome
o DiGeorge Syndrome
o Triploidy

Cancer Diagnosis and Prognosis: Many cancer diagnosis testing kits are available in our company. You can also custom other cancer diagnosis probes according to your needs.

o Bladder Cancer
o Breast Cancer
o Cervical Cancer
o Chronic Lymphocytic Leukemia
o Chronic Granulocytic Leukemia
o Multiple Myeloma

Reagents for FISH: Our optimized reagents and solutions will help you perform your FISH experiments more smoothly and efficiently.

Features: The advantages of our services and products are as follows:

o Simple, easy, fast and repeatable
o Sensitive
o Competitive price
o easy to process multiple slides simultaneously
o High quality

Citations/References [ TOP ]

Andre M. Oliveira, Christopher A. French, Applications of Fluorescence in Situ Hybridization in Cytopathology. Acta Cytol. 2005; 49: 587–594

B. F. Brandriff, L. A. Gordon, B. J. Trask. DNA sequence mapping by fluorescence in situ hybridization. Environmental and Molecular Mutagenesis.2006; 18(4): 259-262

J. Tepperberg, M. J. Pettenati, P. N. Rao et al. Prenatal diagnosis using interphase fluorescence in situ hybridization (FISH): 2-year multi-center retrospective study and review of the literature. Prenat Diagn. 2001; 21: 293–301

Octavian Henegariu, Nyla A. Heerema, et al. Improvements in Cytogenetic Slide Preparation: Controlled Chromosome Spreading, Chemical Aging and Gradual Denaturing. Cytometry 2001; 43: 101-109

Octavian Henegariu, Sevilhan Artan, et al. Cryptic Translocation Identification in Human and Mouse Using Several Telomeric Multiplex FISH. Lab Invest. 2001; 81(4):483-491

Octavian Henegariu, Patricia Bray-Ward, et al. Small Marker Chromosome Identification in Metaphase and Interphase Using Centromeric Multiplex FISH (CM-FISH). Lab Invest. 2001; 81(4):475-481

Octavian Henegariu, Judit Dunai et al. A triple color FISH technique for mouse chromosome identification. Mamm Genome 2001; 12: 462-465

Octavian Henegariu, Nyla A. Heerema, et al. Colour-changing karyotyping: an alternative to M-FISH/SKY. Nature Genet 1999; 23 (3): 263-264

Y S Fan, L M Davis, and T B Shows. Mapping small DNA sequences by fluorescence in situ hybridization directly on banded metaphase chromosomes. Proc Natl Acad Sci U S A. 1990; 87(16): 6223–6227

FISH Probe samples:

Human chromosome 1 painting probe (green) Human chromosome 1 arm painting probe

Human chromosome 1 terminal band painting probe Human chromosome 3 centromere probe

Human chromosome 1 subtelomere probes Hybridization signal of human XIST gene probe (red)

[ TOP ]

TABLE 1: Custom FISH Services
SERVICE	DESCRIPTION	Price
Chromosome/Cell Preparation	We can help you performing cell chromosome FISH (FISH on interphase, metaphase and cultured cells) and tissue chromosome FISH (FISH on formalin-fixed, paraffin-embedded tissue or cell slides).	Contact us
Probes Design, Labeling, Purification and Test	Our well-established standard operating procedure allows efficient optimization of labeling variety of fluorescent probes. Customized probes are available as well. The choice of directly labeled SpectrumOrange, SpectrumGreen, or SpectrumAqua probes is dependent upon the use and combination of other fluorophores in the FISH assay.	Contact us
In Situ Hybridization	We have optimized the FISH hybridization conditions and can provide all kinds of FISH service for researchers.	Contact us
Result Interpretation	Our FISH imaging analysis system consists of a fluorescent microscope, a charge-coupled-device (“CCD”) camera and imaging analysis software. All three components are provided by our component suppliers with internal modifications. Through the use of FISH probes, the imaging analysis system enables medical practitioners to detect and localize the presence or absence of specific DNA sequences in chromosomes.	Contact us

TABLE 2: Premade FISH Probes
Products Name	DESCRIPTION	Price
Mouse chromosome painting probes	Whole chromosome painting probes, please custom the number of the chromosome you wish to paint	Contact us
Human chromosome painting probes	Whole chromosome painting probes, please custom the number of the chromosome you wish to paint	Contact us
CEP8(D8Z2) SpectrmOrange probe	Alpha Satellite DNA , 8p11.1-q11.1	Contact us
CEP12(D12Z3) SpectrumOrange probe	Alpha Satellite DNA Satellite III DNA, Xp11.1-q11.1 Yq12	Contact us
CEP X(DXZ1)/Y (DYZ1)	Alpha Satellite DNA Satellite III DNA, Xp11.1-q11.1 Yq12	Contact us
CEP 1 SpectrumOrange Probe	Satellite II/III DNA, 1q12	Contact us
CEP 2(D2Z1) SpectrumOrange Probe	Alpha Satellite DNA, 2p11.1-q11.1	Contact us
CEP 3(D3Z1) SpectrumOrange Probe	Alpha Satellite DNA, 3p11.1-q11.1	Contact us
CEP 4 SpectrumOrange Probe	Alpha Satellite DNA, 4p11-q11	Contact us
CEP 6(D6Z1) SpectrumOrange Probe	Alpha Satellite DNA, 6p11.1-q11	Contact us
CEP 7(D7Z1) SpectrumOrange Probe	Alpha Satellite DNA, 7p11.1-q11.1	Contact us
CEP 9 SpectrumOrange Probe	Alpha Satellite DNA, 9p11-q11	Contact us
CEP 10 SpectrumOrange Probe	Alpha Satellite DNA, 10p11.1-q11.1	Contact us
CEP 11(D11Z1) SpectrumOrange Probe	Alpha Satellite DNA, 11p11.11-q11	Contact us
CEP 15(D15Z4) SpectrumOrange Probe	Alpha Satellite DNA, 15p11.1-q11.1	Contact us
CEP 16(D16Z3) SpectrumOrange Probe	Alpha Satellite DNA, 15p11.1-q11.1	Contact us
CEP 17(D17Z1) SpectrumOrange Probe	Alpha Satellite DNA, 17p11.1-q11.1	Contact us
CEP 18(D18Z1) SpectrumOrange Probe	Alpha Satellite DNA, 18p11.1-q11.1	Contact us
CEP 20(D20Z1) SpectrumOrange Probe	Alpha Satellite DNA, 20p11.1-q11.1	Contact us
CEP X (DXZ1) SpectrumOrange Probe	Alpha Satellite DNA, Xp11.1-q11.1	Contact us
CEP Y (DYZ1) SpectrumOrange Probe	Satellite III DNA , Yq12	Contact us
HBV Region Probe TAMRA	Probes, dilution buffer and DAPI were included	Contact us
HER-2 Region Probe TAMRA /CEP17	Probes, dilution buffer and DAPI were included	Contact us
EGFR Region Probe TAMRA /CEP7	Probes, dilution buffer and DAPI were included	Contact us
EIF5A2 Region Probe TAMRA/CEP03	Probes, dilution buffer and DAPI were included	Contact us

[ TOP ]

TABLE 3: Custom Diagnosis Detection FISH Kits
Products Name	DESCRIPTION	Price
Prenatal analysis of abnormal number of chromosomes testing kit	Gene location: DLEU1:13q14 DSCR2:21q22 CSP18:18p11.1-q11.1 CSP X: Xp11.1-q11.1 CSP Y: Yp11.1-q11.	Contact us
DiGeorge / Velocardiofacial Syndrome (VCFS) testing kits	Gene location: TUPLE1:22q11 ARSA:22q13	Contact us
Multiple myeloma testing kit	Gene location: RB1:13q14 P53:17p13.1 D13S319:13q14.3 IGH:14q32 1q21	Contact us
Chronic lymphocytic leukemia testing kite	Gene location: CSP 12:12p11.1-q11.1 D13S25:13q14.3 ATM:11q22.3 RB1:13q14 P53:17p13.1	Contact us
Philadelphia chromosome testing kit	Gene location: BCR:22q11.2 ABL:9q34	Contact us
Sex chromosome testing kit	Gene location: CSP X:Xp11.1-q11.1 CSP Y:Yp11.1-q11.1	Contact us
Cervical cytology testing kit	Gene location: TERC:3q26.3 CSP 3:3p11.1-q11.1	Contact us
Bladder cancer testing kit	Gene location: CSP 3:3p11.1-q11.1 CSP 7:7p11.1-q11.1 CSP 17:17p11.1-q11.1 P16:9p21	Contact us
Breast cancer testing kit	Gene location: CSP 17:17p11.1-q11.1 HER-2:17q11.2-q12	Contact us

TABLE 4: FISH Probes for Chromosome Painting

Catalogue No.

Description

Pack Size

Price

1695-B-01

Ready-to-use Human Chromosome Pan-Centromeric paints

Biotin 10 tests

$900

1695-B-02

Concentrated Human Chromosome Pan-Centromeric Paints

Biotin 10 tests

$900

1695-Cy3-01

Ready-to-use Human Chromosome Pan-Centromeric paints

Cy3 10 tests

$900

1695-Cy3-02

Concentrated Human Chromosome Pan-Centromeric Paints

Cy3 10 tests

$900

1695-F-01

Ready-to-use Human Chromosome Pan-Centromeric paints

FITC 10 tests

$900

1695-F-02

Concentrated Human Chromosome Pan-Centromeric Paints

FITC 10 tests

$900

1696-B-01

Ready-to-use Human Chromosome Pan-Telomeric probes

Biotin 10 tests

$900

1696-B-02

Concentrated Human Chromosome Pan-Telomeric Probes

Biotin 10 tests

$900

1696-Cy3-01

Ready-to-use Human Chromosome Pan-Telomeric probes

Cy3 10 tests

$900

1696-Cy3-02

Concentrated Human Chromosome Pan-Telomeric Probes

Cy3 10 tests

$900

1696-F-01

Ready-to-use Human Chromosome Pan-Telomeric probes

FITC 10 tests

$900

1696-F-02

Concentrated Human Chromosome Pan-Telomeric Probes

FITC 10 tests

$900

CPBR-70-002

RTU Human Specific-Centro Probes Biotin Chromosome 2

10 Tests

$900

CPBR-70-003

RTU Human Specific-Centro Probes Biotin Chromosome 3

10 Tests

$900

CPBR-70-006

RTU Human Specific-Centro Probes Biotin Chromosome 6

10 Tests

$900

CPBR-70-007

RTU Human Specific-Centro Probes Biotin Chromosome 7

10 Tests

$900

CPBR-70-008

RTU Human Specific-Centro Probes Biotin Chromosome 8

10 Tests

$900

CPBR-70-009

RTU Human Specific-Centro Probes Biotin Chromosome 9

10 Tests

$900

CPBR-70-00X

RTU Human Specific-Centro Probes Biotin Chromosome X

10 Tests

$900

CPBR-70-00Y

RTU Human Specific-Centro Probes Biotin Chromosome Y

10 Tests

$900

CPBR-70-010

RTU Human Specific-Centro Probes Biotin Chromosome 10

10 Tests

$900

CPBR-70-011

RTU Human Specific-Centro Probes Biotin Chromosome 11

10 Tests

$900

CPBR-70-012

RTU Human Specific-Centro Probes Biotin Chromosome 12

10 Tests

$900

CPBR-70-013

RTU Human Specific-Centro Probes Biotin Chromosome 13+21

10 Tests

$900

CPBR-70-014

RTU Human Specific-Centro Probes Biotin Chromosome 14+22

10 Tests

$900

CPBR-70-015

RTU Human Specific-Centro Probes Biotin Chromosome 15

10 Tests

$900

CPBR-70-016

RTU Human Specific-Centro Probes Biotin Chromosome 16

10 Tests

$900

CPBR-70-017

RTU Human Specific-Centro Probes Biotin Chromosome 17

10 Tests

$900

CPBR-70-018

RTU Human Specific-Centro Probes Biotin Chromosome 18

10 Tests

$900

CPBR-70-020

RTU Human Specific-Centro Probes Biotin Chromosome 20

10 Tests

$900

CPBR-70-115

RTU Human Specific-Centro Probes Biotin Chromosome 1+5+19

10 Tests

$900

CPBR-73-002

RTU Human Specific-Centro Probes Cy3 Chromosome 2

10 Tests

$900

CPBR-73-003

RTU Human Specific-Centro Probes Cy3 Chromosome 3

10 Tests

$900

CPBR-73-006

RTU Human Specific-Centro Probes Cy3 Chromosome 6

10 Tests

$900

CPBR-73-007

RTU Human Specific-Centro Probes Cy3 Chromosome 7

10 Tests

$900

CPBR-73-008

RTU Human Specific-Centro Probes Cy3 Chromosome 8

10 Tests

$900

CPBR-73-009

RTU Human Specific-Centro Probes Cy3 Chromosome 9

10 Tests

$900

CPBR-73-00X

RTU Human Specific-Centro Probes Cy3 Chromosome X

10 Tests

$900

CPBR-73-00Y

RTU Human Specific-Centro Probes Cy3 Chromosome Y

10 Tests

$900

CPBR-73-010

RTU Human Specific-Centro Probes Cy3 Chromosome 10

10 Tests

$900

CPBR-73-011

RTU Human Specific-Centro Probes Cy3 Chromosome 11

10 Tests

$900

CPBR-73-012

RTU Human Specific-Centro Probes Cy3 Chromosome 12

10 Tests

$900

CPBR-73-013

RTU Human Specific-Centro Probes Cy3 Chromosome 13+21

10 Tests

$900

CPBR-73-014

RTU Human Specific-Centro Probes Cy3 Chromosome 14+22

10 Tests

$900

CPBR-73-015

RTU Human Specific-Centro Probes Cy3 Chromosome 15

10 Tests

$900

CPBR-73-016

RTU Human Specific-Centro Probes Cy3 Chromosome 16

10 Tests

$900

CPBR-73-017

RTU Human Specific-Centro Probes Cy3 Chromosome 17

10 Tests

$900

CPBR-73-018

RTU Human Specific-Centro Probes Cy3 Chromosome 18

10 Tests

$900

CPBR-73-020

RTU Human Specific-Centro Probes Cy3 Chromosome 20

10 Tests

$900

CPBR-73-115

RTU Human Specific-Centro Probes Cy3 Chromosome 1+5+19

10 Tests

$900

CPBR-78-002

RTU Human Specific-Centro Probes FITC Chromosome 2

10 Tests

$900

CPBR-78-003

RTU Human Specific-Centro Probes FITC Chromosome 3

10 Tests

$900

CPBR-78-006

RTU Human Specific-Centro Probes FITC Chromosome 6

10 Tests

$900

CPBR-78-007

RTU Human Specific-Centro Probes FITC Chromosome 7

10 Tests

$900

CPBR-78-008

RTU Human Specific-Centro Probes FITC Chromosome 8

10 Tests

$900

CPBR-78-009

RTU Human Specific-Centro Probes FITC Chromosome 9

10 Tests

$900

CPBR-78-00X

RTU Human Specific-Centro Probes FITC Chromosome X

10 Tests

$900

CPBR-78-00Y

RTU Human Specific-Centro Probes FITC Chromosome Y

10 Tests

$900

CPBR-78-010

RTU Human Specific-Centro Probes FITC Chromosome 10

10 Tests

$900

CPBR-78-011

RTU Human Specific-Centro Probes FITC Chromosome 11

10 Tests

$900

CPBR-78-012

RTU Human Specific-Centro Probes FITC Chromosome 12

10 Tests

$900

CPBR-78-013

RTU Human Specific-Centro Probes FITC Chromosome 13+21

10 Tests

$900

CPBR-78-014

RTU Human Specific-Centro Probes FITC Chromosome 14+22

10 Tests

$900

CPBR-78-015

RTU Human Specific-Centro Probes FITC Chromosome 15

10 Tests

$900

CPBR-78-016

RTU Human Specific-Centro Probes FITC Chromosome 16

10 Tests

$900

CPBR-78-017

RTU Human Specific-Centro Probes FITC Chromosome 17

10 Tests

$900

CPBR-78-018

RTU Human Specific-Centro Probes FITC Chromosome 18

10 Tests

$900

CPBR-78-020

RTU Human Specific-Centro Probes FITC Chromosome 20

10 Tests

$900

CPBR-78-115

RTU Human Specific-Centro Probes FITC Chromosome 1+5+19

10 Tests

$900

1125-YB

Chromosome Y (Heterochromatic) Probe

Biotin 10 tests

$900

1125-YCy3

Chromosome Y (Heterochromatic) Probe

Cy3 10 tests

$900

1125-YF

Chromosome Y (Heterochromatic) Probe

FITC 10 tests

$900

1066-10B-02

Conc Human WCP Biotin Chromosome 10

10 Tests

$900

1066-11B-02

Conc Human WCP Biotin Chromosome 11

10 Tests

$900

1066-12B-02

Conc Human WCP Biotin Chromosome 12

10 Tests

$900

1066-13B-02

Conc Human WCP Biotin Chromosome 13

10 Tests

$900

1066-14B-02

Conc Human WCP Biotin Chromosome 14

10 Tests

$900

1066-15B-02

Conc Human WCP Biotin Chromosome 15

10 Tests

$900

1066-16B-02

Conc Human WCP Biotin Chromosome 16

10 Tests

$900

1066-17B-02

Conc Human WCP Biotin Chromosome 17

10 Tests

$900

1066-18B-02

Conc Human WCP Biotin Chromosome 18

10 Tests

$900

1066-19B-02

Conc Human WCP Biotin Chromosome 19

10 Tests

$900

1066-1B-02

Conc Human WCP Biotin Chromosome 1

10 Tests

$900

1066-20B-02

Conc Human WCP Biotin Chromosome 20

10 Tests

$900

1066-21B-02

Conc Human WCP Biotin Chromosome 21

10 Tests

$900

1066-22B-02

Conc Human WCP Biotin Chromosome 22

10 Tests

$900

1066-2B-02

Conc Human WCP Biotin Chromosome 2

10 Tests

$900

1066-3B-02

Conc Human WCP Biotin Chromosome 3

10 Tests

$900

1066-4B-02

Conc Human WCP Biotin Chromosome 4

10 Tests

$900

1066-5B-02

Conc Human WCP Biotin Chromosome 5

10 Tests

$900

1066-6B-02

Conc Human WCP Biotin Chromosome 6

10 Tests

$900

1066-7B-02

Conc Human WCP Biotin Chromosome 7

10 Tests

$900

1066-8B-02

Conc Human WCP Biotin Chromosome 8

10 Tests

$900

1066-9B-02

Conc Human WCP Biotin Chromosome 9

10 Tests

$900

1066-XB-02

Conc Human WCP Biotin Chromosome X

10 Tests

$900

1066-YB-02

Conc Human WCP Biotin Chromosome Y

10 Tests

$900

1066-10B-01

RTU Human WCP Biotin Chromosome 10

10 Tests

$900

1066-11B-01

RTU Human WCP Biotin Chromosome 11

10 Tests

$900

1066-12B-01

RTU Human WCP Biotin Chromosome 12

10 Tests

$900

1066-13B-01

RTU Human WCP Biotin Chromosome 13

10 Tests

$900

1066-14B-01

RTU Human WCP Biotin Chromosome 14

10 Tests

$900

1066-15B-01

RTU Human WCP Biotin Chromosome 15

10 Tests

$900

1066-16B-01

RTU Human WCP Biotin Chromosome 16

10 Tests

$900

1066-17B-01

RTU Human WCP Biotin Chromosome 17

10 Tests

$900

1066-18B-01

RTU Human WCP Biotin Chromosome 18

10 Tests

$900

1066-19B-01

RTU Human WCP Biotin Chromosome 19

10 Tests

$900

1066-1B-01

RTU Human WCP Biotin Chromosome 1

10 Tests

$900

1066-20B-01

RTU Human WCP Biotin Chromosome 20

10 Tests

$900

1066-21B-01

RTU Human WCP Biotin Chromosome 21

10 Tests

$900

1066-22B-01

RTU Human WCP Biotin Chromosome 22

10 Tests

$900

1066-2B-01

RTU Human WCP Biotin Chromosome 2

10 Tests

$900

1066-3B-01

RTU Human WCP Biotin Chromosome 3

10 Tests

$900

1066-4B-01

RTU Human WCP Biotin Chromosome 4

10 Tests

$900

1066-5B-01

RTU Human WCP Biotin Chromosome 5

10 Tests

$900

1066-6B-01

RTU Human WCP Biotin Chromosome 6

10 Tests

$900

1066-7B-01

RTU Human WCP Biotin Chromosome 7

10 Tests

$900

1066-8B-01

RTU Human WCP Biotin Chromosome 8

10 Tests

$900

1066-9B-01

RTU Human WCP Biotin Chromosome 9

10 Tests

$900

1066-XB-01

RTU Human WCP Biotin Chromosome X

10 Tests

$900

1066-YB-01

RTU Human WCP Biotin Chromosome Y

10 Tests

$900

1153-10Cy3-02

Conc Human WCP Cy3 Chromosome 10

10 Tests

$900

1153-11Cy3-02

Conc Human WCP Cy3 Chromosome 11

10 Tests

$900

1153-12Cy3-02

Conc Human WCP Cy3 Chromosome 12

10 Tests

$900

1153-13Cy3-02

Conc Human WCP Cy3 Chromosome 13

10 Tests

$900

1153-14Cy3-02

Conc Human WCP Cy3 Chromosome 14

10 Tests

$900

1153-15Cy3-02

Conc Human WCP Cy3 Chromosome 15

10 Tests

$900

1153-16Cy3-02

Conc Human WCP Cy3 Chromosome 16

10 Tests

$900

1153-17Cy3-02

Conc Human WCP Cy3 Chromosome 17

10 Tests

$900

1153-18Cy3-02

Conc Human WCP Cy3 Chromosome 18

10 Tests

$900

1153-19Cy3-02

Conc Human WCP Cy3 Chromosome 19

10 Tests

$900

1153-1Cy3-02

Conc Human WCP Cy3 Chromosome 1

10 Tests

$900

1153-20Cy3-02

Conc Human WCP Cy3 Chromosome 20

10 Tests

$900

1153-21Cy3-02

Conc Human WCP Cy3 Chromosome 21

10 Tests

$900

1153-22Cy3-02

Conc Human WCP Cy3 Chromosome 22

10 Tests

$900

1153-2Cy3-02

Conc Human WCP Cy3 Chromosome 2

10 Tests

$900

1153-3Cy3-02

Conc Human WCP Cy3 Chromosome 3

10 Tests

$900

1153-4Cy3-02

Conc Human WCP Cy3 Chromosome 4

10 Tests

$900

1153-5Cy3-02

Conc Human WCP Cy3 Chromosome 5

10 Tests

$900

1153-6Cy3-02

Conc Human WCP Cy3 Chromosome 6

10 Tests

$900

1153-7Cy3-02

Conc Human WCP Cy3 Chromosome 7

10 Tests

$900

1153-8Cy3-02

Conc Human WCP Cy3 Chromosome 8

10 Tests

$900

1153-9Cy3-02

Conc Human WCP Cy3 Chromosome 9

10 Tests

$900

1153-XCy3-02

Conc Human WCP Cy3 Chromosome X

10 Tests

$900

1153-YCy3-02

Conc Human WCP Cy3 Chromosome Y

10 Tests

$900

1153-10Cy3-01

RTU Human WCP Cy3 Chromosome 10

10 Tests

$900

1153-11Cy3-01

RTU Human WCP Cy3 Chromosome 11

10 Tests

$900

1153-12Cy3-01

RTU Human WCP Cy3 Chromosome 12

10 Tests

$900

1153-13Cy3-01

RTU Human WCP Cy3 Chromosome 13

10 Tests

$900

1153-14Cy3-01

RTU Human WCP Cy3 Chromosome 14

10 Tests

$900

1153-15Cy3-01

RTU Human WCP Cy3 Chromosome 15

10 Tests

$900

1153-16Cy3-01

RTU Human WCP Cy3 Chromosome 16

10 Tests

$900

1153-17Cy3-01

RTU Human WCP Cy3 Chromosome 17

10 Tests

$900

1153-18Cy3-01

RTU Human WCP Cy3 Chromosome 18

10 Tests

$900

1153-19Cy3-01

RTU Human WCP Cy3 Chromosome 19

10 Tests

$900

1153-1Cy3-01

RTU Human WCP Cy3 Chromosome 1

10 Tests

$900

1153-20Cy3-01

RTU Human WCP Cy3 Chromosome 20

10 Tests

$900

1153-21Cy3-01

RTU Human WCP Cy3 Chromosome 21

10 Tests

$900

1153-22Cy3-01

RTU Human WCP Cy3 Chromosome 22

10 Tests

$900

1153-2Cy3-01

RTU Human WCP Cy3 Chromosome 2

10 Tests

$900

1153-3Cy3-01

RTU Human WCP Cy3 Chromosome 3

10 Tests

$900

1153-4Cy3-01

RTU Human WCP Cy3 Chromosome 4

10 Tests

$900

1153-5Cy3-01

RTU Human WCP Cy3 Chromosome 5

10 Tests

$900

1153-6Cy3-01

RTU Human WCP Cy3 Chromosome 6

10 Tests

$900

1153-7Cy3-01

RTU Human WCP Cy3 Chromosome 7

10 Tests

$900

1153-8Cy3-01

RTU Human WCP Cy3 Chromosome 8

10 Tests

$900

1153-9Cy3-01

RTU Human WCP Cy3 Chromosome 9

10 Tests

$900

1153-XCy3-01

RTU Human WCP Cy3 Chromosome X

10 Tests

$900

1153-YCy3-01

RTU Human WCP Cy3 Chromosome Y

10 Tests

$900

1083-10F-02

Conc Human WCP FITC Chromosome 10

10 Tests

$900

1083-11F-02

Conc Human WCP FITC Chromosome 11

10 Tests

$900

1083-12F-02

Conc Human WCP FITC Chromosome 12

10 Tests

$900

1083-13F-02

Conc Human WCP FITC Chromosome 13

10 Tests

$900

1083-14F-02

Conc Human WCP FITC Chromosome 14

10 Tests

$900

1083-15F-02

Conc Human WCP FITC Chromosome 15

10 Tests

$900

1083-16F-02

Conc Human WCP FITC Chromosome 16

10 Tests

$900

1083-17F-02

Conc Human WCP FITC Chromosome 17

10 Tests

$900

1083-18F-02

Conc Human WCP FITC Chromosome 18

10 Tests

$900

1083-19F-02

Conc Human WCP FITC Chromosome 19

10 Tests

$900

1083-1F-02

Conc Human WCP FITC Chromosome 1

10 Tests

$900

1083-20F-02

Conc Human WCP FITC Chromosome 20

10 Tests

$900

1083-21F-02

Conc Human WCP FITC Chromosome 21

10 Tests

$900

1083-22F-02

Conc Human WCP FITC Chromosome 22

10 Tests

$900

1083-2F-02

Conc Human WCP FITC Chromosome 2

10 Tests

$900

1083-3F-02

Conc Human WCP FITC Chromosome 3

10 Tests

$900

1083-4F-02

Conc Human WCP FITC Chromosome 4

10 Tests

$900

1083-5F-02

Conc Human WCP FITC Chromosome 5

10 Tests

$900

1083-7F-02

Conc Human WCP FITC Chromosome 7

10 Tests

$900

1083-9F-02

Conc Human WCP FITC Chromosome 9

10 Tests

$900

1083-XF-02

Conc Human WCP FITC Chromosome X

10 Tests

$900

1083-11F-01

RTU Human WCP FITC Chromosome 11

10 Tests

$900

1083-12F-01

RTU Human WCP FITC Chromosome 12

10 Tests

$900

1083-13F-01

RTU Human WCP FITC Chromosome 13

10 Tests

$900

1083-14F-01

RTU Human WCP FITC Chromosome 14

10 Tests

$900

1083-15F-01

RTU Human WCP FITC Chromosome 15

10 Tests

$900

1083-16F-01

RTU Human WCP FITC Chromosome 16

10 Tests

$900

1083-17F-01

RTU Human WCP FITC Chromosome 17

10 Tests

$900

1083-18F-01

RTU Human WCP FITC Chromosome 18

10 Tests

$900

1083-19F-01

RTU Human WCP FITC Chromosome 19

10 Tests

$900

1083-1F-01

RTU Human WCP FITC Chromosome 1

10 Tests

$900

1083-20F-01

RTU Human WCP FITC Chromosome 20

10 Tests

$900

1083-21F-01

RTU Human WCP FITC Chromosome 21

10 Tests

$900

1083-22F-01

RTU Human WCP FITC Chromosome 22

10 Tests

$900

1083-2F-01

RTU Human WCP FITC Chromosome 2

10 Tests

$900

1083-3F-01

RTU Human WCP FITC Chromosome 3

10 Tests

$900

1083-4F-01

RTU Human WCP FITC Chromosome 4

10 Tests

$900

1083-5F-01

RTU Human WCP FITC Chromosome 5

10 Tests

$900

1083-6F-01

RTU Human WCP FITC Chromosome 6

10 Tests

$900

1083-7F-01

RTU Human WCP FITC Chromosome 7

10 Tests

$900

1083-9F-01

RTU Human WCP FITC Chromosome 9

10 Tests

$900

1083-XF-01

RTU Human WCP FITC Chromosome X

10 Tests

$900

1083-YF-01

RTU Human WCP FITC Chromosome Y

10 Tests

$900